Specimens containing metals prone to sublimation (high vapor pressure metals)
Sublimating large quantities of metal causes vapor-deposition onto the QMS analytical tube, vacuum gauges, and viewport windows, potentially leading to performance degradation or catastrophic system failure.

Furthermore, because these metals also vapor-deposit onto the chamber interior walls and internal components, the surface cleanliness of the chamber degrades, which significantly increases outgassing. In such cases, meticulous cleaning of the chamber inner walls or component replacement becomes necessary.

Particular caution is required for Zinc (Zn) and Magnesium (Mg), which possess exceptionally high vapor pressures and sublimate even at low temperatures.

Examples of high vapor pressure metals: Zn, Mg, Pb, In, Mn, Ga, Ag, Sn, Al, Cu, etc. Specimens containing halogens
When chemical components containing halogens (especially fluorine) are desorbed, the halogens linger and accumulate inside the main process chamber and detector assembly, causing long-term degradation.
Specimens containing organic compounds
Heating a large volume of organic compounds above their decomposition threshold induces thermal decomposition. The resulting decomposition products scatter and heavily contaminate the interior of the main chamber and the detector array. This necessitates main chamber bakeout operations, manual cleaning, or complete component replacement.
Specimens that release large volumes of gas
Even if the desorbed components do not inherently contaminate the system, measuring a specimen that releases a volume of gas exceeding the permissible pressure limit of the Turbo Molecular Pump (TMP) or the QMS will cause critical damage or failure to these high-vacuum components.


Pre-measurement Recommendations
When measuring specimens with a potential risk of system contamination, we highly recommend performing a preliminary baseline measurement under the following defensive protocols:

・Reduce the linear heating rate to a conservative speed (e.g., approximately 10°C/min).
・Utilize the Bar mode or Scan mode to closely monitor mass spectra profiles.
・Minimize the specimen quantity as much as possible.
・If any of the contamination-inducing components or signs listed above are detected during the tracking run, abort the 　sequence and do not increase the temperature any further.